Adrienne W Paton Selected Research

Molecular Chaperones (Chaperone, Molecular)

9/2012	The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling.
1/2011	BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection.

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Adrienne W Paton Research Topics

Disease

17	Infections 12/2019 - 04/2002
15	Hemolytic-Uremic Syndrome 01/2021 - 04/2002
9	Neoplasms (Cancer) 03/2022 - 11/2009
6	Inflammation (Inflammations) 01/2019 - 01/2008
4	Hepatocellular Carcinoma (Hepatoma) 12/2018 - 08/2009
4	Necrosis 08/2013 - 07/2004
3	Breast Neoplasms (Breast Cancer) 03/2022 - 01/2016
3	Diarrhea 01/2016 - 01/2013
3	Thrombosis (Thrombus) 11/2010 - 07/2004
2	Ovarian Neoplasms (Ovarian Cancer) 03/2022 - 12/2019
2	Acute Kidney Injury (Acute Renal Failure) 11/2019 - 01/2014
2	Whooping Cough (Pertussis) 01/2017 - 10/2006
2	Atrophy 09/2014 - 04/2011
2	Edema (Dropsy) 06/2014 - 08/2013
2	Thrombocytopenia (Thrombopenia) 06/2014 - 10/2007
2	Hemolytic Anemia 06/2014 - 10/2007
2	Cholera 11/2013 - 10/2006
2	Melanoma (Melanoma, Malignant) 09/2012 - 10/2010
2	Experimental Arthritis 04/2011 - 07/2009
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 10/2021
1	Colorectal Neoplasms (Colorectal Cancer) 10/2021
1	Glioblastoma (Glioblastoma Multiforme) 01/2021
1	Polycystic liver disease 11/2020
1	Insulin Resistance 11/2020
1	Hemophilia A (Haemophilia) 01/2020
1	Hemorrhage 01/2020
1	Type 2 Diabetes Mellitus (MODY) 11/2019
1	Prediabetic State (Prediabetes) 11/2019
1	Carcinogenesis 10/2019
1	Diabetic Nephropathies (Diabetic Nephropathy) 10/2019
1	Acute Lung Injury 01/2019
1	Osteosarcoma (Osteogenic Sarcoma) 12/2018
1	Cholestasis 12/2018
1	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 04/2017
1	Pneumococcal Infections 04/2017
1	Cardiomegaly (Heart Hypertrophy) 03/2017
1	Virus Diseases (Viral Diseases) 01/2017
1	Mosquito-Borne Diseases 01/2017
1	Escherichia coli Infections 01/2016
1	Rhabdomyosarcoma 01/2016
1	Colonic Neoplasms (Colon Cancer) 10/2015
1	Multiple Myeloma 05/2015
1	Disease Progression 05/2015
1	Alcoholic Fatty Liver 11/2014

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2002
13	Cytotoxins (Cytolysins)IBA 01/2021 - 07/2004
11	Shiga Toxin (Shigella Toxin)IBA 01/2021 - 10/2007
10	Endoplasmic Reticulum Chaperone BiPIBA 10/2019 - 01/2008
3	ThapsigarginIBA 12/2019 - 11/2009
2	Biomarkers (Surrogate Marker)IBA 03/2022 - 01/2016
2	Polysaccharides (Glycans)IBA 03/2022 - 01/2018
2	N-glycolylneuraminic acidIBA 03/2022 - 01/2018
2	N-Acetylneuraminic Acid (Sialic Acid)IBA 03/2022 - 07/2009
2	Peptides (Polypeptides)IBA 01/2022 - 12/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 10/2019
2	DisulfidesIBA 11/2019 - 01/2017
2	VaccinesIBA 12/2017 - 04/2017
2	Bortezomib (Velcade)FDA Link 05/2015 - 10/2010
2	Molecular Chaperones (Chaperone, Molecular)IBA 09/2012 - 01/2011
2	AntibodiesIBA 09/2012 - 04/2002
2	OligosaccharidesIBA 05/2010 - 03/2006
2	Bacterial ToxinsIBA 05/2005 - 07/2004
1	Tumor Biomarkers (Tumor Markers)IBA 03/2022
1	LectinsIBA 03/2022
1	Complement System Proteins (Complement)IBA 03/2022
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 10/2021
1	Temozolomide (Temodar)FDA LinkGeneric 01/2021
1	Insulin ReceptorIBA 11/2020
1	Factor VIII (Coagulation Factor VIII)IBA 01/2020
1	Viral ProteinsIBA 12/2019
1	Protein Kinase CIBA 12/2019
1	IonomycinIBA 12/2019
1	Viral DNAIBA 12/2019
1	ProinsulinIBA 11/2019
1	HoloenzymesIBA 01/2019
1	Taurocholic Acid (Sodium Taurocholate)IBA 12/2018
1	Bile Acids and Salts (Bile Acids)IBA 12/2018
1	CalnexinIBA 12/2018
1	AntigensIBA 04/2017
1	Oxidoreductases (Dehydrogenase)IBA 04/2017
1	alpha-glycerophosphoric acid (sodium glycerophosphate)IBA 04/2017
1	Pertussis ToxinIBA 01/2017
1	Biological ProductsIBA 01/2017
1	Antiviral Agents (Antivirals)IBA 01/2017
1	GTP-Binding Proteins (G-Protein)IBA 01/2017
1	ADP Ribose Transferases (ADP Ribosyltransferase)IBA 01/2017
1	Carrier Proteins (Binding Protein)IBA 01/2016
1	human ERBB2 proteinIBA 01/2016
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2016
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 11/2014
1	AcidsIBA 11/2014
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 11/2014
1	Amitriptyline (Elavil)FDA LinkGeneric 11/2014

Therapy/Procedure

5	Intraperitoneal Injections 03/2017 - 07/2004
4	Drug Therapy (Chemotherapy) 10/2021 - 10/2015
3	Therapeutics 12/2019 - 10/2015
1	Oncolytic Virotherapy 12/2019
1	Ligation 12/2018